Barbiturate - Barbiturate Barbiturates are drugs that acts as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia. Some also are used as anticonvulsants. Medical uses Today barbiturates are mainly used as anticonvulsants and for the induction of anesthesia. These barbiturates are available in the US: Amobarbital (hypnotic) Aprobarbital (hypnotic) Butabarbital (hypnotic) Butalbital (sedative) Mephobarbital (antianxiety) Pentobarbital (hypnotic) Phenobarbital (anticonvulsant) Secobarbital (hypnotic) Thiobarbital (anesthetic) Barbiturate abuse Barbiturates were very popular in the first half of the 20th century. In moderate amounts, these drugs produce a state of intoxication that is remarkably similar to alcohol intoxication. Symptoms include slurred speech, loss of motor coordination, and impaired judgment. Depending on the dose, frequency, and duration of use,.
Fred Hampton - Edgar Hoover demanded that the COINTELPRO personnel "destroy what the [BPP] stands for" and "eradicate its 'serve the people' programs". Meanwhile, the local Chicago police did not stand idly by. Urged on by the FBI, it launched an all-out assault on the Black Panthers and their allies, characterizing the group as nothing more than a criminal gang. The CPD instigated an unprovoked armed confrontation with party members on July 16, which left one member mortally wounded and six others arrested on serious charges. On July 31, the CPD raided and ransacked the Monroe Street office, smashing typewriters, destroying food and medical supplies for the Panther health clinic and breakfast program, setting several small fires, and beating and arresting a number of Panthers for obstruction. The raid was repeated on October 31..
Benzodiazepine - is discouraged because of tolerance and dependency. Benzodiazepine withdrawal syndrome may be delayed (but less so with short-acting agents) in its onset and longer than barbiturate withdrawal syndrome. The benzodiazepine syndrome is characterized by: insomnia anxiety tremor perspiration loss of appetite delusions As some of the symptoms of the syndrome are identical to the original reasons for the prescription of the drug it may encourage further prescribing. It must be remembered that benzodiazepines are the largest group of misused drugs. [1] Every person on long-term or high dosage of any benzodiazepine should be weaned off the drug. Any abrupt discontinuation may result in confusion, psychosis, convulsions similar to delirium tremens. Benzodiazepines may impair ability to drive vehicles and operate machinery. The impairment is increased by consumption of alcohol. Long-acting benzodiazepine "hang-over".
Sedative - they feel as if they need the drug to function although there is no biological dependence. In both types of dependence, finding and using the drug becomes the focus in life. Both physical and psychological dependence can be treated (see Sedative Dependence). Abuse and Overdoses All sedatives can be abused, but barbiturates are responsible for most of the problems with sedative abuse due to their widespread "recreational" or non-medical use, as well as over-prescribing by medical doctors. People who have difficulty dealing with stress, anxiety or sleeplessness may overuse or become dependent on sedatives. Heroin users take them either to supplement their drug or to substitute for it. Stimulant users frequently take sedatives to calm excessive jitteriness. Others take sedatives recreationally to relax and forget their worries. Barbiturate overdose is a.
Seconal - Seconal Seconal is a trademark name for the barbiturate sodium quinalbarbitone. It was widely used recreationaly in the 1960s and 1970s. Nicknamed "reds", Seconal came in red capsules. Its main medical uses are for seizures, tension relief (as before surgery), and as a temporary sleep aid. It is fairly addictive, and withdrawal symptoms can occur when a continual use is abruptly ended..
Sodium thiopental - Laboratories), thiopental (or thiopentone) sodium) is a short-acting barbiturate drug that induces brief general anesthesia (10-30 minutes) without analgesia by depression of CNS within 60 seconds of injection. Since analgesia is slight, thiopental is only used alone for brief procedures. It is more commonly used to induce hypnosis and anesthesia prior to the use of other anesthetic agents. It is also a radioprotective agent and used in narcotherapy. Along with pancuronium bromide and potassium chloride it is used in some States of the US as part of the lethal injection. In the past it was claimed as a truth drug. Side effects include head ache, retrograde amnesia, emergence delirium, prolonged somnolence and nausea. Its structural name is 5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, empirically it is C11H17O2N2NaS. It was discovered in 1936 by Ernest H..
Stevens Johnson syndrome - with thermal burns, and continued care can only be supportive and symptomatic, there is no specific drug treatment (2002). The cause of SJS is either infections (usually following viral infections such as herpes simplex virus, influenza, mumps, cat-scratch fever, histoplasmosis, Epstein-Barr virus, or similar), drug-induced (penicillins, barbiturate, sulfas, phenytoin), malignancy-related (carcinomas and lymphomas), or idiopathic (50% of the time).
Rachel Roberts - Havana, A Flea in Her Ear, Doctors' Wives, Wild Rovers, O Lucky Man, Murder on the Orient Express, Picnic at Hanging Rock, Yanks and Charlie Chan and the Curse of the Dragon Queen. Roberts committed suicide by barbiturate poisoning in Los Angeles, California..
Pharmacology - Gastrointestinal Tract (see also Digestive system) antacid, reflux suppressant, antiflatulent, antidopaminergic, antispasmodic, proton pump inhibitor, H2 antagonists, cytoprotectant, prostaglandin analogue, laxative, antidiarrhoeal, bile acids For the Cardiovascular System ACE inhibitor, cardiac glycoside, phosphodiesterase inhibitor, nitrate, antiarrhythmic, beta-receptor blocker, antianginal, diuretic, antihypertensive, calcium channel blocker, alpha blocker, vasodilator, peripheral activator, anticoagulant, heparin, antiplatelet drug, fibrinolytic, haemostatic drug, hypolipidaemic agent, statin. For the Central Nervous System hypnotic, anxiolytic, antipsychotic, antidepressant (including tricyclic antidepressants), anti-emetic, anticonvulsant and antiepileptic, movement disorder drug, CNS stimulant, barbiturate, benzodiazepine, cyclopyrrolone, dopamine antagonist, antihistamine, anticholinergic, emetic, cannabinoids, 5-HT antagonist, amphetamine, monoamine oxidase inhibitor, lithium salt, selective serotonin reuptake inhibitor For Pain analgesic, antipyretic, migraine treatment drug NSAIDs, opioid analgesic For Musculo-Skeletal Disorders NSAIDs, muscle relaxant, neuromuscular drug anticholinesterase, COX-2 inhibitor For Endocrine problems androgen, antiandrogen, gonadotropin, corticosteroid, growth hormone,.
William Griffith Wilson - Canada, and his mother moved to Boston, leaving the sickly child with her parents. As a soldier, and then as a businessman, Bill W. drank to alleviate his depressions and to celebrate his Wall Street success. Married in 1918, he and Lois toured the country on a motorcycle and appeared to be a prosperous, promising young couple. By 1933, however, they were living on charity in her parents' house on Clinton Street in Brooklyn, N.Y. Bill had become an unemployable drunk who disdained religion and even panhandled for cash. Inspired by a friend who had stopped drinking, Bill went to meetings of the Oxford Group, an evangelical society founded in Britain by Pennsylvania Frank Buchman. And as Bill underwent a barbiturate-and-belladonna cure called "purge and puke," which was state-of-the-art alcoholism treatment.
Margaret Sullavan - stormy, and two of her three children spent time in mental hospitals. Sullavan herself suffered from depression and began to grow deaf as she grew older, and she was found unconscious in a hotel room from a barbiturate overdose. She died a few days later. Her death was officially ruled an accident, but many think it was a suicide. Her film debut came in 1933 in Only Yesterday. She also appeared in Little Man, What Now, The Good Fairy, So Red the Rose, The Moon's Our Home, Next Time We Love, The Shopworn Angel, Three Comrades (for which she was nominated for the Academy Award for Best Actress), The Shop Around the Corner, The Mortal Storm, Appointment for Love and Cry Havoc. She co-starred frequently with James Stewart, with whom she.
Methaqualone - and respiration. Larger doses can bring about depression, muscular miscoordination and slurred speech. An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, renal insufficiency, coma, and possibly death through cardiac or respiratory arrest. It resembles barbiturate poisoning but with increased motor difficulties and a lower incidence of cardiac or respiratory depression. Toxicity is treated with diazepam and sometimes an anticonvulsant. Methaqualone was discovered by the Indian researcher M. L. Gujiral in 1955 during a antimalarial research program. It was marketed as a sleeping pill from the 1960s under a number of tradenames including Renoval, Melsed and in combination with an antihistamine as Mandrax. From 1965 it was sold on the US market as Quaalude and Sopor, by 1972 it was the sixth most popular sedative in the US. The name Quaalude.
List of artists who died of drug-related causes - popular music, cocaine Rick Dey - of the Vejtables, February Sunshine, the Wilde Knights and the Merry-Go-Round DJ Screw - musician, codeine Tommy Dorsey - jazz musician and bandleader, choked to death while sleeping with the aid of drugs John Dougherty - of Flipper Nick Drake - musician E Jeanne Eagels - actress John Entwistle - of the Who Rick Evers - drummer and songwriter F Chris Farley - comedian Pete Farnden - of the Pretenders Rainer Fassbinder - playwright, director Keith Ferguson - of the Fabulous Thunderbirds Zach Foley - of EMF and Carrie Tom Foote - of the Devices and the Loco Gringos G Rory Gallagher - of Taste Jerry Garcia - of the Grateful Dead, cardiac arrest strongly exacerbated by longtime heroin abuse Paul Gardiner - of Gary.
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