GlaxoSmithKline - GlaxoSmithKline GlaxoSmithKline (GSK) is a pharmaceutical and healthcare company, one of the largest in the world. In 2002 the company had sales of £31.8 billion and made a profit of £6.5 billion. It employs around 100,000 people worldwide, including over 40,000 in sales and marketing. The company is listed on the London and New York Stock Exchanges. Headquartered in Brentford it does the majority of its business in the US but has a presence in almost 70 countries. The company's CEO is Jean-Pierre Garnier (former COO SmithKline Beecham) and the non-executive chairman is Sir Richard Sykes (former chairman of Glaxo Wellcome) and current rector of Imperial College. GSK was formed in December 2000 by a merger between Glaxo Wellcome and SmithKline Beecham, both the product of.
Horlicks - milky hot drink claimed to promote sleep when drunk at bedtime. It is manufactured by GlaxoSmithKline in the United Kingdom and India. The product's name has entered the vernacular due to an advertising campaign in which the word "Horlicks" was used as a substitute profanity (such as, for example "bollocks"); given its original usage in this context however it conveys a much milder connotation than any actual curse. The term was used in July 2003 by British Foreign Secretary Jack Straw to describe irregularities in the preparation and provenance of a dossier regarding weapons of mass destruction in Iraq..
University of the Sciences in Philadelphia - Science became the University of the Sciences in Philadelphia, incorporating the Philadelphia College of Pharmacy, the Misher College of Arts and Sciences, the College of Health Sciences, and the College of Graduate Studies. Notable alumni include the founders and early leaders of Eli Lilly and Company, Wyeth, Johnson & Johnson's McNeil Consumer Products, Burroughs Wellcome and Company (now merged into GlaxoSmithKline), Rorer Pharmaceuticals (now merged into Aventis), and Warner-Lambert Corporation (now merged into Pfizer). Official site: http://www.usip.edu.
AZT - the drug in 1964, under a US National Institutes of Health (NIH) grant. When the viral premise was dropped, AZT essentially disappeared. Years later in February 1985, NIH's Hiroaki Mitsuya demonstrated the drug's effectiveness against HIV, due to its ability to block the action of the "reverse transcriptase" enzyme that HIV uses to replicate its RNA for splicing into the DNA of a target cell. The formula soon purchased by Burroughs-Wellcome (now GlaxoSmithKline), which filed for a patent on AZT in 1986. The Food and Drug Administration approved the drug for use against HIV on March 20, 1987, and then as a preventative treatment in 1990. When it was first administered dosages tended to be much higher then today, typically one 400mg dose every four hours (even at night) and one.
Bupropion HCl - anti-depressant unrelated to tricyclics or SSRIs. The patent is owned by GlaxoSmithKline, who sell the compound as Wellbutrin®. It has been shown to aid cessation of cigarette smoking and is sold for this purpose as Zyban. It also promotes weight loss and does not exacerbate acne. Its exact mode of action is unknown. Side effects include sleepnessness. External Links Wellbutrin Pharmacology, Pharmacokinetics, Studies, Metabolism - Bupropion - RxList Monographs NAMI Wellbutrin This article is a stub. You can help Wikipedia by fixing it..
Succinylcholine chloride - 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethylethanaminium] dichloride. The compound is sold under the trademarked name of Anectine and is manufactured by GlaxoSmithKline. Succinylcholine acts as a depolarizing muscle relaxant. It imitates the action of acetylcholine at the neuromuscular junction, but is not as readily degraded by acetylcholine esterase. The prolonged stimulation of the acetylcholine receptor results first in disorganized muscle contractions, then in profound relaxation. Its medical uses are limited to short-term muscle relaxation in anesthesia and intensive care, usually for facilitation of tracheal intubation. Despite its many undesired effects on the circulatory system and skeletal muscles (including malignant hyperthermia, a rare but life-threatening disease), it is still much used because it arguably has the fastest onset of action of all muscle relaxants. A single intravenous dose of 0.6 to 1.0 milligram per kilogram of body.
Richard Sykes - Society and a trustee of the Natural History Museum (London) and Kew Gardens. He was formerly chairman of GlaxoSmithKline and president of the British Association for the Advancement of Science. He is perhaps best known for leading Glaxo's introduction of the drug Zantac. He holds a PhD in Microbial Biochemistry from Bristol University as well as number of honorary degrees, including ones from the University of Madrid, Cranfield University, Brunel University, Edinburgh University, Hertfordshire University, University of Hull, Huddersfield University, Leeds University, Leicester University, Newcastle University, Sheffield University, Strathclyde University, University of Warwick, University of Westminster, Birmingham University, Nottingham University, Sheffield Hallam University and the University of Surrey. In 1994 he was knighted for his services to the pharmaceutical industry and in 1999 he was awarded the Singapore National Day Public.
Paroxetine - United States) or Seroxat® (in the UK). It was released onto the market in 1992 by the pharmaceutical company GlaxoSmithKline and has since become one of the most successful anti-depressants on the market. It is the second most prescribed anti-depressant in the UK. Paroxetine is in a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) of which Prozac is probably the most well known. Like some other antidepressants, it also can be used in the treating of anxiety disorders. It was the first (and as of 2002, the only) antidepressant formally approved in the United States for the treatment of social phobia, causing it to be sometimes referred to (although inaccurately) as an anti-shyness drug. Although the drug has proved to be extremely helpful in the majority of cases.
Philadelphia, Pennsylvania - is a delightful rural setting in Fairmount Park. David Rittenhouse was a clockmaker and friend of the American Revolution. 8th and Market Streets, 1910s Government From a governmental perspective, Philadelphia County is a legal nullity, as all county functions were assumed by the city in 1952, which has been coterminous with the county since 1854. Historic seal of the city of Philadelphia, made by William Penn. Executive The city is headed by an elected mayor who is limited to two, four-year terms. The incumbent is former Philadelphia City Council President John Street (D), who was first elected in 1999. He was re-elected by a larger majority in 2003. Legislative The legislative branch of Philadephia is the Philadelphia City Council. Judicial The Philadelphia County Court of Common Pleas, also known as the.
Zyban - Zyban Zyban is the GlaxoSmithKline tradename of a bupropion hydrochloride (amfebutamone, Wellbutrin) sustained release tablet. The drug is sold to help people stop smoking tobacco by reducing the severity of withdrawal symptoms. It can be used in combination with nicotine replacement therapies. Bupropion is a tricyclic aminoketone antidepressant and is marketed as the antidepressant Wellbutrin, the sustained release effect was added to create Zyban. Its pathway of effect has not be clearly identified but it is believed to be a monoamine uptake inhibitor, but also has some effect on the dopamine transporter and on norepinephrine uptake. The efficacy over placeboes has been proved in clinical trials with bupropion resulting in a two- or three-fold improvement in abstinence rates. It has a number of common side effects, including dry.
List of pharmaceutical companies - S.A Bayer BioPort Corporation Biovail Boehringer-Ingelheim Pharmaceuticals Bristol-Myers Squibb Byk Gulden Eli Lilly and Company GlaxoSmithKline Ipsen Limited Janssen-Cilag UK, Ltd Janssen-Ortho, Inc Janssen Pharmaceutica Jelfa Knoll AG Krka Pharmaceuticals Menarini Merck & Co. Inc Merck KGaA Novartis Novo Nordisk A/S Pfizer Inc Pharmacia Procter & Gamble Ranbaxy Pharmaceuticals USA Inc Roche Sanofi-Synthelabo Schering Health Care, Ltd Servier Laboratories Solvay Group Takeda Pharmaceuticals Inc Wyeth Yamanouchi Pharmaceutical See also: Lists of companies.
List of British companies - BOC (formerly Brin Oxygen Company, British Oxygen Company) British Airways British Rail Cameron Balloons Civil_Aviation_Authority Easyjet GKN plc GlaxoSmithKline Go Fly Limited HSBC ICI Jardine Matheson J Sainsbury (formally J Sainsbury and Son) Kangol Laura Ashley Lloyds TSB plc Marconi plc (formerly The General Electric Company plc) Marks and Spencer plc MG Rover Group Orange Railtrack Rolls Royce Royal Bank of Scotland Save a Cup Recycling Company Shell Oil (Anglo-Dutch) Tate & Lyle Tesco Triumph Motor Company Unilever (Anglo-Dutch) Vestey Group Virgin Atlantic Airways Vodafone W H Smith (formally W H Smith and Son) Woolworths Xrefer Former companies, including acquired and merged ones Acorn, Ltd, acquired by Olivetti AEI Austin Blue Star Line British Aerospace East India Company British Leyland Motor Corporation British Motor Corporation British Motor Holdings British Thomson-Houston Company.
List of major companies in Philadephia - or doing business in Philadelphia include: Aramark (catering and hospitality) GlaxoSmithKline (pharmaceuticals) Comcast (cable television, telecommunications, and sports holdings) CIGNA (insurance and financial services) Crown Cork & Seal Keystone Blue Cross/Pennsylvania Blue Shield (insurance services) Pep Boys (automotive parts and services) Sunoco (oil refining) Tasty Baking Company (makers of Tastykake pies and cakes) Verizon (formerly Bell Atlantic) (telecommunications).
