Viagra - Viagra Viagra is a drug used to treat male erectile dysfunction (impotence), developed by the pharmaceutical company Pfizer. The generic name for this compound is sildenafil citrate. The pills are blue with the words "Pfizer" on one side and "VGR xx" (with xx being either 25, 50 or 100 as the miligram dose of that pill) on the other. Table of contents showTocToggle("show","hide") 1 History 2 Chemistry 3 Mechanism of action 4 Contraindications and side effects 5 Dosage and price History Viagra was initially developed to treat heart disease (angina). In trial studies, the penile erection enhancing effects were noticed. The drug was patented in 1996, approved by the FDA on March 27, 1998 (becoming the first pill approved to treat erectile disfunction in the United.
Impotence - intervention for a number of different conditions may remove anatomical structures necessary to erection, damage nerves, or impair blood supply. Treatment depends on the cause. Testosterone supplements may be used for cases with hormonal deficiency. However, usually the cause is lack of adequate penile blood supply as a result of age-dependent damage of inner walls of blood vessels. Previously, medical substances were used to be directly injected into the erectile tissue of penile shaft to treat impotence. In some cases refractory to the medical treatment, a penile implant (penile prosthesis) could be advised. After the discovery of orally active agents that increase the efficacy of NO, which dilates the blood vessels of corpora cavernosa, more conservative methods were started to be used. Sildenafil citrate (Viagra) is an oral agent that blocks.
Ferid Murad - oxide as a signalling molecule in the cardiovascular system. But, Salvador Moncada from Honduras claims to have made this discovery before the Nobel Prize laureates. See also: Nobel Prize, Viagra..
Erection - the outflow. As blood flows in, the penis stiffens, its girth and length increases, and it rises to an angle that can vary from horizontal to almost vertical. Normally, the foreskin retracts and exposes the glans. When the erection mechanism fails to function properly, the result is impotence. Impotence in humans is treated with prosthetic devices, and with prescription drugs. Some prescription drugs are injected directly into the corpus cavernosum or used as urethral suppositories, directly causing erection even in the absence of sexual excitation, while others, such as Viagra, are taken orally and support erection that is due to sexual excitation. Both an erection and the absence of an erection can be embarrassing, depending on circumstances. An erection may be embarrassing: if the man or boy does not want to.
1998 - suspect in an Alabama abortion clinic bombing. February 18 - Two white separatists were arrested in Nevada and accused of plotting a biological attack on New York City subways. February 20 - Iraq disarmament crisis: Iraqi President Saddam Hussein negotiates a deal with U.N. secretary-general Kofi Annan, allowing weapons inspectors to return to Baghdad, preventing military action by the U.S. and Britain. February 23 - Tornadoes in central Florida destroy or damage 2,600 structures and kill 42. February 28 - Serbian police begin to wipe out so-called "terrorist gangs" in Kosovo. March 2 - Data sent from the Galileo probe indicates that Jupiter's moon Europa has a liquid ocean under a think crust of ice. March 4 - Gay rights: The Supreme Court of the United States rules that federal laws.
Tadalafil - selling points: It works for up to 36 hours after being swallowed and can be taken with or without food. It has the same mode of action as Viagra, and Levitra. Lilly, of Indianapolis, and ICOS, of Bothell, Washington, will sell Cialis in the United States for a wholesale price of $8.10 a pill. Cialis has a multiyear promotional deal with professional golf. Cialis has FDA approval and is scheduled to appear in U.S. stores in December, 2003. External Links Cialis Drug Information - Approved by FDA - USA This article is a stub. You can help Wikipedia by fixing it..
Aphrodisiac - trade in rhinoceros horn that is endangering this animal. (See Carl Hiaasen's 1997 novel Sick Puppy.) There is some debate in scientific circles as to whether a chemical present in chocolate is an aphrodisiac. see also Viagra\n.
Black widow spider - longer legs. Though its venom is toxic, deaths from Latrodectus bites are rare, only sixty-three reported in the United States between 1950 and 1959 (Miller, 1992). According to a widely reported media story (Wigmore, 2003), Chilean scientists were using part of Latrodectus venom to synthesize a drug that will not only serve as a male contraceptive, but will also work in a fashion similar to Viagra, however this has not been reported in any mainstream peer-reviewed scientific journal. Sources Miller, T. 1992. Latrodectism: bite of the black widow spider. Am. Fam. Phys. 45:181 Wigmore, B. 2003. Venom 'Viagra'. The Mirror. News section, p.31.
Bob Dole - 1975. He was reelected to the Senate in 1980, 1986 and again in 1992 (serving from January 3, 1969, to June 11, 1996). In 1996 he resigned to devote his efforts to his Presidential campaign ending his leadership as Majority Leader (1985 - 1987), and earlier as 1995 - 1996 Minority Leader 1987 - 1995; Chairman of the Committee on Finance (1981 - 1985), Special Committee on Security and Cooperation in Europe (1985 - 1987); unsuccessful Republican candidate for Vice President of the United States in 1976; unsuccessful candidate for the Republican Presidential nomination in 1988; unsuccessful Republican nominee for President of the United States in 1996; engaged in the practice of law in Washington, DC, (1997 -). Following his unsuccessful Presidential campaign, Dole became a television commercial spokesman for such.
The Human Stain - also the local press. Suddenly, at the height of his trouble, his vigorous wife Iris dies of a stroke. Silk is devastated and accuses those who have been persecuting him as murderers. It takes him about two years to calm down and adapt to the new situation: being retired and single. He wants Zuckerman, who is a professional author, to write a book about the whole affair, but the latter refuses. So Silk spends several months writing an account he calls Spooks himself, but when he has finished he realizes that it is not really intended for publication. Nevertheless the two men become friends. Gradually, we learn about Coleman Silk´s past. As a young man, even during the first years of his marriage to Iris, he was a womanizer. Now, as.
Sandwich, England - Pfizer, a US pharmaceuticals company, which has built a research & development centre near Sandwich, employing over 1,500 people. Viagra, Pfizer's treatment for erectile dysfunction, was discovered here. The town's connection with the snack of the same name is that John Montagu, 4th Earl of Sandwich allegedly invented it; see his entry for further details. There is another village in Kent called Ham Street, or just Ham. A road sign some miles away pointing to both villages, thus: Ham Sandwich has had to be replaced several times because people keep stealing it..
Sexual revolution - tradition and the rise of attitudes that were accepting of greater sexual freedom and experimentation that spread all over the world and captured in the phrase free love. This was a perhaps a throwback to over 2,000 years ago during the times of ancient Greece and Rome that provided the Graeco-Roman component of Western culture. During those times there was a different sexual and moral code. There were specific gods of love like the Greek Eros, from whom the word "erotic" is derived, and the Roman Cupid, who is the center of the modern Valentine's Day. In Greek mythology these characters seduced, romanced, made love, lusted, cheated, and even raped each other in very graphic and colorful ways. This can be contrasted with the teachings of the Christian Church. The power.
Sextasy - a colloquial name for a combination of two drugs ecstasy and Viagra (sildenafil). This drug is increasingly popular among clubgoers and on the rave scene. Use can be dangerous - there have been reports of heart problems. Apart from that it is believed that this drug promotes risky sexual behaviour. Further reading The 'sextasy' craze. Clubland's dangerous party mix: Viagra and ecstasy Newsweek. 2002 Jun 3;139(22):30..
Sound symbolism - Kukai, the founder of Shingon wrote his Sound, word, reality in the 9th_century which relates all sounds to the voice of the Dharmakaya Buddha. (more to come: in the meantime see: Mantra) Early Western Phonosemantics The idea of phonosemantics was sporadically discussed during the Middle Ages and the Renaissance. In 1698, Locke wrote against the idea in an essay called An Essay on Human Understanding. His argument was that if there were any connection between sounds and ideas, then we would all be speaking the same language, but this is an over-generalisation. In 1676 Leibniz published his book New Essays on Human Understanding which contains a point by point critique of Locke's essay. Leibnez picks up on the generalization used by Locke and adopts a less rigid approach: clearly there is.
Rafael Palmeiro - his stride until after the age of 30, when he began a streak of hitting 30-plus home runs and batting in 100-plus runs nine seasons in a row (1995-2003). He has the greatest number of career home runs for a player who never led his league in that category. Palmeiro appears in Viagra commercials..
Pfizer Inc. - antifungal medication Diflucan, the long-acting antibiotic Zithromax and the well-known impotence drug Viagra. It is named after chemist Charles Pfizer (1824-1906) In 2002, Pfizer merged with competitor Pharmacia. Table of contents showTocToggle("show","hide") 1 Bjork-Shiley Heart Valve 2 Patients' Rights Legislation 3.
Poppers - of heat and excitement that can last for several minutes. According to the National Institute on Drug Abuse, use of these drugs is associated with unsafe sexual practices that greatly increase the risk of contracting and spreading infectious diseases such as HIV/AIDS and hepatitis. Chronic inhalant use may result in serious and sometimes irreversible damage to the user's heart, liver, kidneys, lungs, and brain. Brain damage may result in personality changes, diminished cognitive functioning, memory impairment, and slurred speech. Death from inhalant use can occur after a single use or after prolonged use. Sudden sniffing death (SSD) may result within minutes of inhalant use from irregular heart rhythm leading to heart failure. Other causes of death include asphyxiation, aspiration, or suffocation. The combination of nitrites with Viagra, another sex-enhancing drug sometimes.
Priapism - which may necessitate amputation. Treatment is usually hydraulic, withdrawing a part of the trapped blood. This is a medical emergency (urological) and needs proper treatment by a qualified medical practitioner. Priapism is not associated with sexual intercourse or sexual thoughts. Priapism can be caused by certain drugs, such as anti-depressants and Viagra, and can be a possible sign of a spinal injury. Conditions that thicken the blood, or affect the red blood cells, such as leukaemia and sickle-cell anaemia can cause this problem. The name comes from the god Priapus, referring to that god's most notable attribute. The female counterpart is known as clitorism. See also paraphimosis.
New London, Connecticut - from the town of Groton, Connecticut, home of a United States Navy submarine base and of Electric Boat, aka "EB", builder of nuclear-powered submarines. As world research headquarters of the pharmaceutical giant Pfizer, New London and Groton have therefore given birth to Viagra, among other drugs. New London lies on Interstate 95, roughly half-way between New Haven, Connecticut and Providence, Rhode Island. Ferries also transport cars and people between New London and Orient Point, at the northeastern tip of Long Island, as well as Fishers Island, a small island lying closest to New London but belonging to New York State. New London was the birthplace of sculptor Edward Clark Potter. Geography According to the United States Census Bureau, the city has a total area of 27.9 km˛ (10.8 mi˛). 14.3 km˛.
Nitrate - carbohydrates, nitrates can form a flammable or even explosive mixture. For example, potassium nitrate is the oxidizing ingredient in black gunpowder. In Medicine, Nitrates such as nitroglycerin and isosorbide mono- and di- nitrates are particularly useful for prevention and treatment of angina pectoris. However they can cause a dangerous reaction if taken within 24 hrs of taking Viagra or sildenafil citrate. Nitrates covered in Wikipedia include: ammonium nitrate lead (II) nitrate potassium nitrate silver nitrate sodium nitrate Nitrates should not be confused with nitrites, the salts of nitrous acid..
